Table 2.
Target pathways identified by KEGG enrichment.
| Map name | Map ID | Input number | Input proteins | P value |
|---|---|---|---|---|
| Pathways in cancer | K05200 | 8 | Q02750|P31749|P50150|P25445|P06753|Q9Y4K3|Q15147|P11166 | 1.45E − 08 |
| Thyroid hormone signaling pathway | K04919 | 5 | P11166|Q02750|P31749|Q15147|P49815 | 3.03E − 07 |
| mTOR signaling pathway | K04150 | 5 | Q02750|Q8TB45|P49815|P31749|Q96B36 | 7.88E − 07 |
| Adrenergic signaling in cardiomyocytes | K04261 | 5 | Q15173|P31749|P06753|Q9BXT2|Q15147 | 1.04E − 06 |
| p53 signaling pathway | K04115 | 4 | P25445|P27701|P31350|P49815 | 1.32E − 06 |
| PI3K-Akt signaling pathway | K04151 | 6 | Q02750|P31749|P50150|P22105|Q15173|P49815 | 2.55E − 06 |
| Chagas disease (American trypanosomiasis) | K05142 | 4 | P25445|P31749|Q9Y4K3|Q15147 | 1.06E − 05 |
| MAPK signaling pathway | K04010 | 5 | P31749|P25445|Q02750|Q9BXT2|Q9Y4K3 | 1.09E − 05 |
| Cholinergic synapse | K04725 | 4 | Q02750|P31749|P50150|Q15147 | 1.32E − 05 |
| Sphingolipid signaling pathway | K04071 | 4 | Q15173|Q02750|P31749|Q15147 | 1.44E − 05 |
| AMPK signaling pathway | K04152 | 4 | Q15173|P49815|P31749|Q96B36 | 1.59E − 05 |
| Dopaminergic synapse | K04728 | 4 | Q15173|P31749|P50150|Q15147 | 2.26E − 05 |
| Phospholipase D signaling pathway | K04072 | 4 | Q02750|P31749|Q15147|P49815 | 2.91E − 05 |
| Chemokine signaling pathway | K04062 | 4 | Q02750|P31749|P50150|Q15147 | 7.69E − 05 |
P value < 0.05, the number of target proteins involved in the pathway ≥4.