Figure 5.

Photomicrography of the immunostaining and immunolabeled area (μm²) for NF-κB (a, b), TGF-β1 (c, d), FGF-2 (e, f), and collagen III (g, h) in the border and central region of rats' hyperglycemic wounds treated with Lanette, insulin 0.5 U/g, or lupeol 0.2% for 14 days. ^∗ p < 0.05, ^∗∗ p < 0.01, and ^∗∗∗ p < 0.001 vs. Lanette group. ^# p < 0.05 vs. insulin group, using ANOVA followed by the Newman-Keuls test. Bar represents 20 μm. Black arrows indicate antibody staining against NF-κB, TGF-β1, FGF-2, and collagen III. Lu 0.2% = lupeol 0.2%.