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. 2019 May 16;11:117. doi: 10.3389/fnagi.2019.00117

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Copyright © 2019 Tanner, Amin, Hardcastle, Parvataneni, Vaillancourt, Mareci and Price.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Image shows regions of change in fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD; calculated as the mean of λ₂ and λ₃), axial diffusivity (AD; calculated as λ₁), λ₂ (L2), and λ₃ (L3). The green regions are the white matter skeleton created by TBSS. Blue indicates regions where post > pre. Non-surgery participants had no areas of significant change while surgery participants had extensive change (FSL randomise paired t-test with 5000 permutations).