TABLE 1.

Demographic, brain, and cognitive scores by group.

	TKA	Non-TKA
	(n = 61)	(n = 65)
Age	$69.13\pm 7.02,60-85$	$68.63\pm 5.59,60-83$
Education	$15.36\pm 2.85,10-23$	$16.05\pm 2.65,9-24$
Race (Black:White)	8:53	4:61
PreMRI pain	$10.78\pm 18.14,0-75$	$8.12\pm 15.47,0-70$
PostMRI pain**	$38.67\pm 23.53,0-100$	$7.60\pm 10.27,0-40$
MED	$11.97\pm 10.99,0-37.50$	–
Brain integrity	$-0.05\pm 0.74,$-$2.05-1.07$	$0.04\pm 0.62,$-$1.79-1.14$
Cognitive reserve**	$0.34\pm 0.63,$-$0.84-1.84$	$0.69\pm 0.56,$-$1.20-1.88$
Processing speed**	$-0.04\pm 0.54,$-$1.27-1.29$	$0.26\pm 0.68,$-$1.74-1.84$
Immediate memory**	$-0.36\pm 0.74,$-$1.90-1.20$	$0.10\pm 0.88,$-$1.65-2.02$
Delay memory**	$-0.21\pm 0.79,$-$2.00-1.06$	$0.21\pm 0.71,$-$2.17-1.40$

**p < 0.01. PreMRI Pain, participant-reported pain (0–100 scale) during the baseline MRI; PostMRI Pain, participant-reported pain (0–100 scale) during the follow-up MRI; MED, morphine equivalent dose. Brain integrity is a z-score composite of ventricle volume, leukoaraiosis volume, and entorhinal cortex thickness. Cognitive reserve is a composite of word reading ability, vocabulary knowledge, and years of education. Processing speed is a composite of stroop word reading total correct in 45 s, digit symbol raw score in 120 s, trail making test, Part A total time in seconds. Immediate memory is a composite of Hopkins verbal learning test – revised (HVLT) trial 1 total words recalled and Rey–Osterrieth complex figure immediate recall. Delay memory is a composite of Hopkins verbal learning test – revised (HVLT) delay recall and retention and Rey–Osterrieth complex figure delay recall.