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. 2019 May 16;10:854. doi: 10.3389/fimmu.2019.00854

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Copyright © 2019 Fernandes, Oliveira, Brüggemann, Sato, Olivo and Arantes-Costa.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Physical exercise decreases pro-inflammatory cytokines and increases anti-inflammatory cytokines in the lungs of OVA-sensitized animals. The mean values (±SE) obtained in the pulmonary homogenate of (A) IL-4 (*p < 0.001 and 0.023, respectively when compared EX or OVA to the SAL group and #p = 0.035 compared to the OVA group), (B) IL-6 (*p = 0.008 compared to the SAL group and #p = 0.035 compared to the OVA group), (C) TGF-β and (D) IL-10 (*p = 0.001 compared to the SAL group and #p = 0.035 compared to the OVA group). N = 10 per group.