A‐Elgayoum 2009.

Clinical features and settings	Presenting signs and symptoms: Clinically suspected malaria Previous treatment for malaria: No exclusions based on previous treatment. Information on previous treatment collected, but actual data not provided. Clinical setting: Primary healthcare facilities Country: Khartoum state, central Sudan Malaria endemicity: Seasonal and low Malaria endemic species:P. falciparum
Participants	Sample size: 410 Age: All age groups eligible. Mean age 21 years. Sex: Both males and females eligible. Actual proportions of males and females in the participant population not stated. Co‐morbidities and pregnancy: No exclusion criteria based on co‐morbidities or pregnancy. No details of the frequency of these conditions in the participant population is presented. Parasite density of microscopy positive cases: Not presented
Study design	Enrolment was consecutive and prospective. One RDT was evaluated.
Target condition and reference standard(s)	Target condition: Malaria parasitaemia Reference standard: Microscopy thick and thin blood films Person(s) performing microscopy: Expert malaria microscopist Microscopy setting: Quality Assurance Laboratory Number of high power fields examined before declaring negative: 300 Number of observer or repeats: Not stated Resolution of discrepancies between observers: Not stated
Index and comparator tests	Commerical name of RDT: Paracheck Pf (Orchid Biomedical Systems, Goa, India) Parasite(s) designed to detect:P. falciparum Designated Type: Type 1 Batch numbers: Not stated Transport and storage conditions: Not stated Person(s) performing RDT: Technicians RDT setting: Primary healthcare facilities
Follow‐up	Not applicable
Notes	Source of funding: PhD financial support from the Ministry of Higher Education and Scientific Research
Table of Methodological Quality
Item	Authors' judgement	Description
Representative spectrum? All tests	Yes	Participants were a consecutive sample of people presenting at healthcare facilities with clinically suspected malaria
Acceptable reference standard? All tests	Unclear	Unclear how many observer repeats were used, but the microscopy was described as the 'gold standard'
Partial verification avoided? All tests	Yes	All participants who received the index test also received the reference test
Differential verification avoided? All tests	Yes	The same reference test was used regardless of the index test results
Incorporation avoided? All tests	Yes	The index test does not form part of the reference standard
Reference standard results blinded? All tests	Yes	Reported that the tests were performed blindly
Index test results blinded? All tests	Yes	Reported that the tests were performed blindly
Uninterpretable results reported? All tests	Unclear	Number enrolled in the study was explicitly stated and corresponded to the number presented in the analysis; therefore no withdrawals due to invalid results
Withdrawals explained? All tests	Yes	Number enrolled in the study was explicitly stated and corresponded to the number presented in the analysis; therefore no withdrawals