Bojang 1999.
Clinical features and settings |
Presenting signs and symptoms: Temperature of 37.5 °C or higher, or a recent history of fever Previous treatment for malaria: No exclusions based on previous treatment and no information presented on previous treatment, except for those with false positive results on RDT Clinical setting: Malaria outpatient clinic Country: The Gambia (Basse, Upper River Division) Malaria endemicity: Not stated Malaria endemic species:P. falciparum |
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Participants |
Sample size: 139 Age: Inclusion criteria stipulated all were children; actual age range not stated Sex: Not mentioned either as an inclusion criteria or a characteristic of included participants Co‐morbidities and pregnancy: Not mentioned either as an inclusion criteria or a characteristic of included participants Parasite density of microscopy positive cases: Not presented |
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Study design | Enrolment was prospective. The sampling method was not described. One RDT was evaluated. | |
Target condition and reference standard(s) |
Target condition: Malaria parasitaemia Reference standard: Microscopy thick blood smear Person(s) performing microscopy: Not stated Microscopy setting: Not stated Number of high power fields examined before declaring negative: Not stated Number of observer or repeats: Not stated Resolution of discrepancies between observers: Not applicable |
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Index and comparator tests |
Commerical name of RDT: ParaSight‐F (Beckton Dickinson, Franklin Lakes, NJ, US) Parasite(s) designed to detect:P. falciparum Designated Type: Type I Batch numbers: Not stated Transport and storage conditions: Not stated Person(s) performing RDT: Field staff who had attended three training session RDT setting: Malaria clinic |
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Follow‐up | Not applicable | |
Notes | Source of funding: Medical Research Council Laboratories, The Gambia | |
Table of Methodological Quality | ||
Item | Authors' judgement | Description |
Representative spectrum? All tests | Unclear | All participants were attending a malaria clinic with fever or history of fever, but the sampling method was not described |
Acceptable reference standard? All tests | Unclear | Not details given of the microscopy process |
Partial verification avoided? All tests | Yes | All participants who received the index test also received the reference test |
Differential verification avoided? All tests | Yes | The same reference test was used regardless of the index test results |
Incorporation avoided? All tests | Yes | The index test does not form part of the reference standard |
Reference standard results blinded? All tests | Unclear | Blinding not described |
Index test results blinded? All tests | Yes | "Test performed without reference to the results of the corresponding thick blood smear" |
Uninterpretable results reported? All tests | Unclear | The number of participants enrolled was explicitly stated and corresponded to the number presented in the analysis; therefore there were no participants excluded due to invalid results |
Withdrawals explained? All tests | Yes | The number of participants enrolled was explicitly stated and corresponded to the number presented in the analysis; therefore there were no withdrawals |