Fernando 2004.

Clinical features and settings	Presenting signs and symptoms: Fever or history of fever Previous treatment for malaria: No exclusions because of prior antimalarial use, and no data presented on the frequency of recent antimalarial use in the participants Clinical setting: A malaria research station and a malaria clinic Country: Sri Lanka Malaria endemicity: Not stated Malaria endemic species:P. vivax (70%) and P. falciparum
Participants	Sample size: 328 Age: All ages above five years eligible; mean age 28.3 years (range 5 to 72 years) Sex: Both males and females eligible; 64% of the participants were males Co‐morbidities and pregnancy: No exclusion criteria based on co‐morbidities or pregnancy. No details of the frequency of these conditions in the participant population is presented. Parasite density of microscopy positive cases: Not presented
Study design	Enrollment was consecutive and prospective. One RDT was evaluated.
Target condition and reference standard(s)	Target condition: Malaria parasitaemia Reference standard: Microscopy thick and think blood films Person(s) performing microscopy: Trained microscopists Microscopy setting: At the clinics and in a laboratory Number of high power fields examined before declaring negative: 400 Number of observer or repeats: Two independent readers; one at the clinics and another in a laboratory Resolution of discrepancies between observers: There were no discrepancies between the two microscopists
Index and comparator tests	Commerical name of RDT: ICT Malaria Pf/Pv (Amrad‐ICT, Sydney, Australia) Parasite(s) designed to detect:P. falciparum or mixed infection, non‐falciparum malaria species only Designated Type: Type 2 Batch numbers: Not stated Transport and storage conditions: Stored and used at room temperature, which often exceeds 30 °C Person(s) performing RDT: The researchers RDT setting: At the clinics
Follow‐up	Not applicable
Notes	Source of funding: National Science Foundation, Sri Lanka
Table of Methodological Quality
Item	Authors' judgement	Description
Representative spectrum? All tests	Yes	Participants were a consecutive sample of people attending clinics with fever or history of fever
Acceptable reference standard? All tests	Yes	Twp independent trained microscopists viewed 400 high power fields before declaring a slide negative
Partial verification avoided? All tests	Yes	All participants who received the index test also received the reference test
Differential verification avoided? All tests	Yes	The same reference test was used regardless of the index test results
Incorporation avoided? All tests	Yes	The index test does not form part of the reference standard
Reference standard results blinded? All tests	Unclear	Blinding not described
Index test results blinded? All tests	Unclear	Blinding not described
Uninterpretable results reported? All tests	Unclear	The number of participants enrolled was clearly stated, and the number included in the analysis corresponds to this number, indicating no withdrawals
Withdrawals explained? All tests	Yes	The number of participants enrolled was clearly stated, and the number included in the analysis corresponds to this number, indicating no withdrawals