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. 2011 Jul 6;2011(7):CD008122. doi: 10.1002/14651858.CD008122.pub2

Gaye 1999.

Clinical features and settings Presenting signs and symptoms: Malaria symptoms
Previous treatment for malaria: Not mentioned, either as an exclusion criteria or characteristic of included participants
Clinical setting: Outpatient clinic
Country: Senegal (North Senegal, Richard‐Toll)
Malaria endemicity: Not stated
Malaria endemic species: Not stated
Participants Sample size: 182
Age: All ages eligible. Actual age range 1 to 55 years
Sex: Not mentioned, either as an inclusion criteria or characteristic of included participants
Co‐morbidities and pregnancy: Not mentioned, either as an inclusion criteria or characteristic of included participants
Parasite density of microscopy positive cases: Not presented
Study design Enrollment was prospective. The sampling method was not described. One test was evaluated.
Target condition and reference standard(s) Target condition: Malaria parasitaemia
Reference standard: Microscopy thick blood film
Person(s) performing microscopy: Not stated
Microscopy setting: Not stated
Number of high power fields examined before declaring negative: Not stated
Number of observer or repeats: Not stated
Resolution of discrepancies between observers: Not applicable
Index and comparator tests Commerical name of RDT: PATH Falciparum Malaria
Parasite(s) designed to detect:P. falciparum
Designated Type: Type 1
Batch numbers: Not stated
Transport and storage conditions: Not described
Person(s) performing RDT: Not stated
RDT setting: Not stated
Follow‐up Not applicable
Notes Source of funding: Not stated
Table of Methodological Quality
Item Authors' judgement Description
Representative spectrum? 
 All tests Unclear All participants were presenting to an outpatient clinic with malaria symptoms, but the sampling method was not described
Acceptable reference standard? 
 All tests Unclear Not details given of the microscopy process
Partial verification avoided? 
 All tests Yes All participants who received the index test also received the reference test
Differential verification avoided? 
 All tests Yes The same reference test was used regardless of the index test results
Incorporation avoided? 
 All tests Yes The index test does not form part of the reference standard
Reference standard results blinded? 
 All tests Unclear Blinding not described
Index test results blinded? 
 All tests Unclear Blinding not described
Uninterpretable results reported? 
 All tests Unclear The numbers of participants originally enrolled in the study was clearly stated, and corresponds to the number presented in the analysis; therefore there were no exclusions due to invalid test results
Withdrawals explained? 
 All tests Yes The numbers of participants originally enrolled in the study was clearly stated, and corresponds to the number presented in the analysis; therefore there were no withdrawals