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. 2011 Jul 6;2011(7):CD008122. doi: 10.1002/14651858.CD008122.pub2

Kumar 1996.

Clinical features and settings Presenting signs and symptoms: Febrile patients
Previous treatment for malaria: No exclusion criteria based on prior use of antimalarials; relevant data collected but presented only for false positives
Clinical setting: Clinic of the Malaria Research Centre
Country: India (Goa)
Malaria endemicity: Not stated
Malaria endemic species:P. vivax andP. falciparum
Participants Sample size: 98
Age: Not mentioned, either as an inclusion criteria or characteristic of included participants
Sex: Not mentioned, either as an inclusion criteria or characteristic of included participants
Co‐morbidities and pregnancy: Not mentioned, either as an exclusion criteria or characteristic of included participants
Parasite density of microscopy positive cases: Not presented
Study design Enrollment was prospective. The sampling method was not described. One RDT was evaluated.
Target condition and reference standard(s) Target condition: Malaria parasitaemia
Reference standard: Microscopy thick and thin blood smears
Person(s) performing microscopy: Not stated
Microscopy setting: Clinic of the Malaria Research Centre
Number of high power fields examined before declaring negative: Not stated
Number of observer or repeats: Not stated
Resolution of discrepancies between observers: Not applicable
Index and comparator tests Commerical name of RDTs: ICT Malaria‐Pf (ICT Diagnostics, Brookvale, NSW, Australia)
Parasite(s) designed to detect:P. falciparum
Designated Type: Type 1
Batch numbers: Not stated
Transport and storage conditions: Stored at 4 °C prior to use
Person(s) performing RDT: Not stated
RDT setting: Clinic of the Malaria Research Centre
Follow‐up Not applicable
Notes Source of funding: Not stated
Table of Methodological Quality
Item Authors' judgement Description
Representative spectrum? 
 All tests Unclear All participants were attending a Malaria Research Clinic with fever; however the sampling method was not described
Acceptable reference standard? 
 All tests Unclear The microscopy process was not described
Partial verification avoided? 
 All tests Yes All participants who received the index test also received the reference test
Differential verification avoided? 
 All tests Yes The same reference test was used regardless of the index test results
Incorporation avoided? 
 All tests Yes The index test does not form part of the reference standard
Reference standard results blinded? 
 All tests Unclear Blinding not described
Index test results blinded? 
 All tests Unclear Blinding not described
Uninterpretable results reported? 
 All tests Unclear The numbers of participants originally enrolled in the study was not clearly stated; therefore it is unclear whether there were any exclusions due to invalid test results
Withdrawals explained? 
 All tests Unclear The numbers of participants originally enrolled in the study was not clearly stated; therefore it is unclear whether there were any withdrawals