Kumar 2004.
Clinical features and settings |
Presenting signs and symptoms: Fever Previous treatment for malaria: No mention of previous treatment for malaria, either as an exclusion criteria or a characteristic of included participants Clinical setting: Primary health centres Country: India (Karnataka state) Malaria endemicity: Not stated Malaria endemic species: Mainly P. falciparum, some P. vivax |
|
Participants |
Sample size: 2891 Age: Not mentioned either as an exclusion criteria or a characteristic of included participants Sex: Not mentioned either as an exclusion criteria or a characteristic of included participants Co‐morbidities and pregnancy: Not mentioned either as an exclusion criteria or a characteristic of included participants Parasite density of microscopy positive cases: Not presented |
|
Study design | Enrollment was prospective. The sampling method was not described. One RDTs was evaluated. | |
Target condition and reference standard(s) |
Target condition: Malaria parasitaemia Reference standard: Microscopy thick and thin blood film Person(s) performing microscopy: Laboratory technicians Microscopy setting: Initially undertaken at the primary health centres and later cross‐checked at the Central Malaria Laboratory Number of high power fields examined before declaring negative: Not stated Number of observer or repeats: Two Resolution of discrepancies between observers: Not described |
|
Index and comparator tests |
Commerical name of RDT: Paracheck‐Pf (Orchid Biomedical Systems, Goa, India) Parasite(s) designed to detect:P. falciparum Designated Type: Type 1 Batch numbers: Not stated Transport and storage conditions: Stored at 4 °C and brought to room temperature before performing the test Person(s) performing RDT: Not stated RDT setting: Not stated |
|
Follow‐up | Not applicable | |
Notes | Source of funding: Not stated | |
Table of Methodological Quality | ||
Item | Authors' judgement | Description |
Representative spectrum? All tests | Unclear | All participants were attending health centres with fever, but the sampling methods were not described |
Acceptable reference standard? All tests | Unclear | Two independent microscopists read the slides; however the number of high power fields viewed before declaring a slide negative was not stated |
Partial verification avoided? All tests | Yes | All participants who received the index test also received the reference test |
Differential verification avoided? All tests | Yes | The same reference test was used regardless of the index test results |
Incorporation avoided? All tests | Yes | The index test does not form part of the reference standard |
Reference standard results blinded? All tests | Unclear | Blinding not described |
Index test results blinded? All tests | Unclear | Blinding not described |
Uninterpretable results reported? All tests | Unclear | The numbers of participants originally enrolled in the study was not clearly stated; therefore it is unclear whether there were any exclusions due to invalid test results |
Withdrawals explained? All tests | Unclear | The numbers of participants originally enrolled in the study was not clearly stated; therefore it is unclear whether there were any withdrawals |