Mwanza 2005.

Clinical features and settings	Presenting signs and symptoms: Fever Previous treatment for malaria: Not mentioned, either as an exclusion criteria or characteristic of included participants Clinical setting: Outpatient clinics Country: Zambia (copper belt, Ndola and Kitwe) Malaria endemicity: Not stated Malaria endemic species: Not stated
Participants	Sample size: 119 Age: Inclusion criteria: adults and children aged over 60 months Sex: Not reported, no mention of sex as inclusion or exclusion criteria Co‐morbidities and pregnancy: Not reported, no mention of these conditions as inclusion or exclusion criteria Parasite density of microscopy positive cases: Not presented
Study design	Enrollment was prospective. The sampling method was not described. One RDT was tested.
Target condition and reference standard(s)	Target condition: Malaria parasitaemia Reference standard: Microscopy Person(s) performing microscopy: Not stated Microscopy setting: Not stated Number of high power fields examined before declaring negative: Not stated Number of observer or repeats: Not stated Resolution of discrepancies between observers: Not applicable
Index and comparator tests	Commerical name of RDT: Hexagon Malaria Parasite(s) designed to detect:P. falciparum Designated Type: Type 1 Batch numbers: Not stated Transport and storage conditions: Not described Person(s) performing RDT: Not stated RDT setting: Not stated
Follow‐up	Not applicable
Notes	Source of funding: Not stated
Table of Methodological Quality
Item	Authors' judgement	Description
Representative spectrum? All tests	Unclear	Participants were all attending outpatient clinics with fever, however the sampling method was not described
Acceptable reference standard? All tests	Unclear	Microscopy process is not described
Partial verification avoided? All tests	Yes	All participants who received the index test also received the reference test
Differential verification avoided? All tests	Yes	The same reference test was used regardless of the index test results
Incorporation avoided? All tests	Yes	The index test does not form part of the reference standard
Reference standard results blinded? All tests	Unclear	Blinding not described
Index test results blinded? All tests	Unclear	Blinding not described
Uninterpretable results reported? All tests	Unclear	The number of participants originally enrolled in the study was not clearly stated, therefore it is unclear whether there were any exclusions due to invalid test results
Withdrawals explained? All tests	Unclear	The number of participants originally enrolled in the study was not clearly stated, therefore it is unclear whether there were any withdrawals