2. Detailed search strategies.
| Search set | CIDG SR^ | CENTRAL | MEDLINE^^ | EMBASE^^ | LILACS^^ |
| 1 | Shigell* | Shigell* | Shigell* | Shigell$ | Shigell* |
| 2 | Dysentery | DYSENTERY, BACILLARY | DYSENTERY, BACILLARY | SHIGELLOSIS | Dysentery |
| 3 | 1 or 2 | 1 or 2 | 1 or 2 | DYSENTERY | 1 or 2 |
| 4 | antibiotic* | ANTI‐BACTERIAL AGENTS/THERAPEUTIC USE | ANTI‐BACTERIAL AGENTS/THERAPEUTIC USE | 1 or 2 or 3 | antibiotic* |
| 5 | tetracycline* | ANTI‐INFECTIVE AGENTS/THERAPEUTIC USE | ANTI‐INFECTIVE AGENTS/THERAPEUTIC USE | tetracycline$ | tetracycline* |
| 6 | chloramphenicol | antibiotic* | antibiotic* | chloramphenicol | chloramphenicol |
| 7 | ampicillin* | tetracycline* | tetracycline* | ampicillin | ampicillin |
| 8 | co‐trimoxazole | chloramphenicol | chloramphenicol | co‐trimoxazole | co‐trimoxazole |
| 9 | fluoroquinolone* | ampicillin | ampicillin | fluoroquinolone$ | fluoroquinolone* |
| 10 | quinolone* | co‐trimoxazole | co‐trimoxazole | quinolone$ | quinolone* |
| 11 | norfloxacin | fluoroquinolone* | fluoroquinolone* | norfloxacin | norfloxacin |
| 12 | ciprofloxacin | quinolone* | quinolone* | ciprofloxacin | ciprofloxacin |
| 13 | ofloxacin | norfloxacin | norfloxacin | ofloxacin | ofloxacin |
| 14 | azithromycin | ciprofloxacin | ciprofloxacin | azithromycin | azithromycin |
| 15 | ceftriaxone | ofloxacin | ofloxacin | ceftriaxone | ceftriaxone |
| 16 | nalidixic acid | azithromycin | azithromycin | nalidixic acid | nalidixic acid |
| 17 | pivmecillinam | ceftriaxone | ceftriaxone | rifaximin | rifaximin |
| 18 | 4‐17/or | nalidixic acid | nalidixic acid | cefixime | cefixime |
| 19 | 3 and 18 | rifaximin | rifaximin | trimethoprim‐sulfamethoxazole | trimethoprim‐sulfamethoxazole |
| 20 | — | cefixime | cefixime | antibiotic$ | pivmecillinam |
| 21 | — | trimethoprim‐sulfamethoxazole | trimethoprim‐sulfamethoxazole | pivmecillinam | 4‐20/or |
| 22 | — | pivmecillinam | pivmecillinam | 5‐21/or | 3 and 21 |
| 23 | — | 4‐22/or | 4‐22/or | Limit 22 to human | — |
| 24 | — | 3 and 23 | 3 and 23 | — | — |
| 25 | — | — | Limit 24 to human | — | — |
^Cochrane Infectious Diseases Group Specialized Register. ^^Search terms used in combination with the search strategy for retrieving trials developed by The Cochrane Collaboration (Higgins 2006); upper case: MeSH or EMTREE heading; lower case: free text term.