1. Detailed search strategies.
| Search set | CIDG SRa | CENTRAL | MEDLINEb | EMBASEb | NLM Gatewayb | Web Science Citationb | LILACSb |
| 1 | artemotil | artemotil | artemotil | artemotil | artemotil | artemotil | artemotil |
| 2 | arteether | arteether | artemotil | arteether | arteether | arteether | arteether |
| 3 | beta arteether | beta arteether | artemotil | beta arteether | beta arteether | beta arteether | 1 or 2 |
| 4 | alpha arteether | alpha arteether | alpha arteether | alpha arteether | alpha arteether | alpha arteether | — |
| 5 | artecef | artecef | artecef | artecef | artecef | artecef | — |
| 6 | E‐MAL | 1 or 2 or 3 or 4 or 5 | E‐MAL | E‐MAL | E‐MAL | E‐MAL | — |
| 7 | malaria | malaria | 1 or 2 or 3 or 4 or 5 or 6 | 1 or 2 or 3 or 4 or 5 or 6 | 1 or 2 or 3 or 4 or 5 or 6 | 1 or 2 or 3 or 4 or 5 or 6 | — |
| 8 | — | 6 and 7 | Exp MALARIA | Exp MALARIA | Exp MALARIA | Malaria | — |
| 9 | — | — | 7 and 8 | 7 and 8 | 7 and 8 | 7 and 8 | — |
| 10 | — | — | Limit to human | Limit to human | — | — | — |
aCochrane Infectious Diseases Group Specialized Register. bSearch terms used in combination with the search strategy for retrieving trials developed by The Cochrane Collaboration (Lefebvre 2008); upper case: MeSH or EMTREE heading; lower case: free text term.