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. 2019 May 16;7:197. doi: 10.3389/fped.2019.00197

Figure 3.

Figure 3

The box plots illustrate the mean, 25th and 75th percentiles, and 2SD boundaries of the plasma zonulin levels in children on no immunosuppressive medications (n = 43) vs. steroids alone (n = 20) vs. Steroids plus another immunosuppressive medication (n = 51) The dashed line indicates-the mean+2SD plasma zonulin level in healthy adult control participants. One sample t-test of No immunosuppressive medications vs. healthy controls (mean = 10.2; SD = 2.5): p < 0.001. One sample t-test of Steroids alone vs. healthy controls (mean = 10.2; SD = 2.5): p = 0.06. One sample t-test of Steroids + Any other IST vs. healthy controls (mean = 10.2; SD = 2.5): p < 0.001. SD, Standard deviation; IST, immunosuppressive therapy.