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. 2010 Mar 17;2010(3):CD000215. doi: 10.1002/14651858.CD000215.pub4

Gongora‐Rivera 2006.

Methods Randomized controlled trial
Duration: between November 1999 and January 2001
Participants Number: 36 enrolled (14 male, 22 female)
Inclusion criteria: adults with subarachnoid and intraventricular cysticercosis
Exclusion criteria: concurrent disease that contraindicated corticosteroid, albendazole allergy, previous cysticidal or surgical treatment for neurocysticercosis in the previous 3 months, pregnant or lactating women, neurological diseases affecting function, unable to attend for regular follow up, Karnofsky score ≤ 50 points
Type of lesion: degenerating, viable, or mixed
Interventions Group 1. Intravenous dexamethasone: 8 mg every 8 hours for 4 days followed by 15 mg per kg albendazole for 1 day
 Group 2. Intravenous dexamethasone: 8 mg every 8 hours for 4 days followed by 30 mg per kg albendazole for 1 day
Outcomes Included in the review: symptom severity score at baseline and 7 days; adverse events associated with treatment
Not included in the review: reduction in cyst volume at 90 days
Notes Location: Mexico
Source of funding: not stated
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Low risk Quote: "...a computer‐generated randomization plan"
Decision: done
Allocation concealment? Low risk Quote: "The code of the two different albendazole doses was available in sealed envelopes and was not opened until the trial completion"
Blinding? 
 All outcomes Low risk Quote: "For blinding the pharmaceutical laboratory...provided according to a computer‐generated randomization plan, tablets containing 200 mg or 400 mg albendazole with identical appearance. Neither the patient nor the study staff were aware of treatment assignment"
Decision: done
Incomplete outcome data addressed? 
 All outcomes Low risk Inclusion of randomized participants in the analysis: 36 randomized, 5 did not compete the study (86%). An intention‐to‐treat analysis was also undertaken with similar results obtained.
Free of selective reporting? Low risk No evidence of selective reporting
Free of other bias? Low risk No evidence of other bias