Padma 1994.
Methods | Randomized controlled trial Duration: dates not specified. Participants followed up for 3 months |
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Participants | Number: 75 enrolled (52 male, 23 female) Inclusion criteria: adults and children aged 3.5 to 50 years with epilepsy, parenchymal single small enhancing lesions Exclusion criteria: neurological deficit on examination Type of lesion: non‐viable |
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Interventions | Group 1. Albendazole: 15 mg per kg per day for 7 days Group 2. Placebo | |
Outcomes | Included in the review: complete resolution, partial resolution, and no resolution of lesion at 1 week, 1 month and 3 months | |
Notes | Location: India Source of funding: not stated |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Unclear risk | Quote: "Patients were randomly allocated to placebo or albendazole therapy" Decision: unclear, probably done |
Allocation concealment? | Unclear risk | Not described Decision: unclear |
Blinding? All outcomes | Low risk | Quote: "CTs were assessed by a neuroradiologist who was not aware of the treatment received by the patient" Placebos were used for participants Decision: done |
Incomplete outcome data addressed? All outcomes | Low risk | 75 participants randomized, follow‐up data at 3 months available for 68 (91%) |
Free of selective reporting? | Low risk | No evidence of selective reporting |
Free of other bias? | Low risk | No evidence of other bias |