Padma 1995.
Methods | Randomized controlled trial Duration: dates not specified. Participants followed up for 3 months. |
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Participants | Number: 29 enrolled (22 male, 7 female) Inclusion criteria: adults and children aged 8 to 50 with multiple cystic lesions suggestive of neurocysticercosis plus neurological signs Exclusion criteria: calcified lesions only Type of lesion: degenerating, viable or mixed (possible to follow the radiological clearance of individual lesions by type) |
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Interventions | Group 1. Albendazole: 15 mg per kg per day for 7 days Group 2. Placebo | |
Outcomes | Included in the review: change in number of lesions at 1 and 3 months; persistence of lesions at 1 week, 1 month, and 3 months Not included in the review: change in oedema at 1 and 3 months |
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Notes | Location: India Source of funding: not stated |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Unclear risk | Quote: "We undertook a randomized, double‐blind, placebo‐controlled study" Decision: unclear, probably done |
Allocation concealment? | Unclear risk | Not described Decision: unclear |
Blinding? All outcomes | Low risk | Quote: "...double‐blind, placebo‐controlled study"... "Placebo tablets of similar appearance"..."The CTS scans were assessed...by a neuroradiologist who was not aware of the treatment given" Decision: done |
Incomplete outcome data addressed? All outcomes | Low risk | 29 randomized, 29 included in the analysis (100%) |
Free of selective reporting? | Low risk | No evidence of selective reporting |
Free of other bias? | Low risk | No evidence of selective reporting |