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. 2006 Jul 19;2006(3):CD004390. doi: 10.1002/14651858.CD004390.pub2

Gonzalez 1988.

Methods Randomized controlled trial
Length of follow up: 24 h
Withdrawals and losses to follow up: none
Score on Jadad scale: 1
Participants Number of participants: 200
Inclusion criteria: inpatients aged 1 day to 5 years with diarrhea for < 15 days and signs of dehydration; in the IV group, 78/100 were mildly and 22/100 were moderately dehydrated; in the ORT group, 85/100 were mildly, 14/100 were moderately, and 1 was severely dehydrated
Exclusion criteria: received previous treatment; referrals from other institutions; shock; septicemia; paralytic ileus; and abdominal distension
Interventions 1. IV (100 participants): mildly dehydrated get 150 to 180 mL/kg/24 h; moderately dehydrated get IV for 1 h at 20 to 30 mL/kg, then 200 to 250 mL/kg/24 h
 2. ORT (100 participants): WHO/UNICEF solution; mildly dehydrated received 75 mL/kg for 6 h; moderately dehydrated received 150 mL/kg for 6 h
 ORS administered orally, and nasogastric if required
Outcomes 1. Duration of diarrhea
 2. Complications
 3. Sodium concentration
 4. Failures (not defined)
Notes Trial location: Mexico
Source of funding: not stated