Kuschner 1995.
Methods | Randomised, double‐blind, placebo‐controlled trial Method of randomisation not stated Patients kept a daily diary of symptoms and timing of medication doses Patients were seen daily for at least 3 days and then on day 10 |
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Participants | 79 US military personnel participating in a military exercise in Thailand during May 1993 Entry criteria: three or more liquid bowel movements per 24 hour period; or two liquid stools plus cramps, nausea, vomiting, or fever; diarrhoea of no more than 48 hours' duration |
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Interventions | Treatment: Azithromycin 500 mg orally daily for three days Comparison: Ciprofloxacin 500 mg orally daily for three days Both groups: Doxycycline daily as malaria prophylaxis |
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Outcomes | 1. Clinical cure: resolution of diarrhoea and all symptoms within 72 hours after taking first dose of study medication 2. Treatment failure: persistency of diarrhoea or any symptom for longer than 72 hours after treatment was initiated | |
Notes |