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. 2000 Jul 24;2000(3):CD002242. doi: 10.1002/14651858.CD002242

Kuschner 1995.

Methods Randomised, double‐blind, placebo‐controlled trial
Method of randomisation not stated
Patients kept a daily diary of symptoms and timing of medication doses
Patients were seen daily for at least 3 days and then on day 10
Participants 79 US military personnel participating in a military exercise in Thailand during May 1993
Entry criteria: three or more liquid bowel movements per 24 hour period; or two liquid stools plus cramps, nausea, vomiting, or fever; diarrhoea of no more than 48 hours' duration
Interventions Treatment: Azithromycin 500 mg orally daily for three days
Comparison: Ciprofloxacin 500 mg orally daily for three days
Both groups: Doxycycline daily as malaria prophylaxis
Outcomes 1. Clinical cure: resolution of diarrhoea and all symptoms within 72 hours after taking first dose of study medication
 2. Treatment failure: persistency of diarrhoea or any symptom for longer than 72 hours after treatment was initiated
Notes