Bunnag THI 89‐90.
Methods | Randomised, method not specified No exclusions reported Loss to follow‐up at day 28: AM480 = 7/53 (13%), AM600 = 3/53 (7%) |
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Participants | 106 Thai male adults 15 to 45 years Febrile Severe malaria (WHO 1990b) Asexual falciparum parasitaemia |
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Interventions | AMim480 vs AMim600: 1. AM480: 160 mg on day 1, 80 mg on days 2 to 5 2. AM600: 200 mg on day 1, 100 mg on days 2 to 5 Patients with Pv during 28 d follow‐up given 150 mg chloroquine base | |
Outcomes | 1. FCT 2. PCT 3. Cure rate at day 28 4. Recrudescence (WHO 1973) | |
Notes | Quality assessment: B, B, B Arthermin |