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. 1998 Jul 27;1998(3):CD000527. doi: 10.1002/14651858.CD000527

Bunnag THI 89‐90.

Methods Randomised, method not specified
No exclusions reported
Loss to follow‐up at day 28: AM480 = 7/53 (13%), AM600 = 3/53 (7%)
Participants 106 Thai male adults
15 to 45 years
Febrile
Severe malaria (WHO 1990b)
Asexual falciparum parasitaemia
Interventions AMim480 vs AMim600:
 1. AM480: 160 mg on day 1, 80 mg on days 2 to 5
 2. AM600: 200 mg on day 1, 100 mg on days 2 to 5
 
 Patients with Pv during 28 d follow‐up given 150 mg chloroquine base
Outcomes 1. FCT
 2. PCT
 3. Cure rate at day 28
 4. Recrudescence (WHO 1973)
Notes Quality assessment: B, B, B
Arthermin