Karbwang THI 91.
Methods | Randomised, method not specified No exclusions or loss to follow‐up reported |
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Participants | 26 Thai adults (25 male) 15 to 45 years Severe falciparum malaria (WHO 1990b). Excluded: antimalarials in previous 24 h |
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Interventions | AMim vs QNNiv: 1. AM: 160 mg on day 1, 80 mg on days 2 to 7) 2. QNN: 20 mg/kg on day 1, 10 mg/kg every 8 h to day 7 | |
Outcomes | 1. Mortality by day 7 2. FCT 3. PCT 4. Time to recover conciousness 5. Neurological sequelae 6. Adverse effects | |
Notes | Quality assessment: B, B, C Arthermin (80 mg ampule) |