Anh VNM 89.
Methods | Random number table; open Excluded = 6/47 (13%; < 1000 Pf/µl) Follow‐up: 7 to 14 days hospitalisation No loss to follow‐up reported |
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Participants | 41 Vietnamese adults 16 to 52 years Cerebral malaria (Choray coma scale 3, equivalent Glasgow 3‐6) with or without renal, gastrointestinal, hepatic or pulmonary complications Pf >1000/µl |
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Interventions | ASiv vs QNNiv: 1. AS240: 60 mg at 0 h, 4 h, 24 h and 48 h 2. QNN (20 mg/kg over 4 h then 10 mg/kg every 8 h to day 7) | |
Outcomes | 1. Mortality 2. Coma recovery time 3. PCT (50, 95 & 100%) | |
Notes | Quality assessment: B, A, C AS: Guilin No.2 Pharmaceutical Factory, China; supplied by Roche Asian Research Foundation |