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. 1998 Jul 27;1998(3):CD000527. doi: 10.1002/14651858.CD000527

Anh VNM 89.

Methods Random number table; open
Excluded = 6/47 (13%; < 1000 Pf/µl)
Follow‐up: 7 to 14 days hospitalisation
No loss to follow‐up reported
Participants 41 Vietnamese adults
16 to 52 years
Cerebral malaria (Choray coma scale 3, equivalent Glasgow 3‐6) with or without renal, gastrointestinal, hepatic or pulmonary complications
Pf >1000/µl
Interventions ASiv vs QNNiv:
 1. AS240: 60 mg at 0 h, 4 h, 24 h and 48 h
 2. QNN (20 mg/kg over 4 h then 10 mg/kg every 8 h to day 7)
Outcomes 1. Mortality
 2. Coma recovery time
 3. PCT (50, 95 & 100%)
Notes Quality assessment: B, A, C
AS: Guilin No.2 Pharmaceutical Factory, China; supplied by Roche Asian Research Foundation