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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: J Intensive Care Med. 2018 Jul 9;34(5):364–373. doi: 10.1177/0885066618784861

Table 1.

Composition of common sepsis resuscitation fluids

Crystalloid Colloid
Human Hydroxyethyl starch Gelatin
Plasma 0.9%
Sodium
Chloride
Lactated
Ringer’s
Hartmann’s
Solution
PlasmaLyte /
Normosol-R
4%
Albumin
20%
Albumin
10%
(200/0.5)
(Hemohes)
6%
(450/0.7)
(Hextend)
6%
(130/0.4)
(Voluven)
6%
(130/0.4)
(Volulyte)
6%
(130/0.42)
(Venofundin)
6%
(130/0.42)
(Tetraspan)
4%
Succinylated
Gelatin
(Gelofusine)
3.5%
Urea-Linked
Gelatin
(Haemaccel)
Sodium 135–145 154 130 131 140 140 48–100 154 143 154 137 154 140 154 145
Potassium 3.5–5.0 4.0 5.4 5.0 3.0 4.0 4.0 5.1
Calcium 2.2–2.6 1.5 1.8 2.5 2.5 6.3
Magnesium 0.8–1.0 1.5 0.5 1.5 1.0
Chloride 94–111 154 109 112 98 128 154 124 154 110 154 118 120 145
Acetate 27 34 24
Lactate 1–2 28 28 28
Malate 5.0
Gluconate 23
Bicarbonate 23–27
Octanoate 6.4 32
Osmolarity 291 308 273 277 294 250 210–260 310 307 308 286 309 296 274 301

All values are given in mmol/L except osmolarity, which is in mOsm/L. Electrolyte concentrations of intravenous fluid preparations may differ by manufacturer: information is given for lactated Ringer’s (Baxter, Deerfield, IL, USA), Hartmann solution (B. Braun Melsungen AG, Melsungen, Germany), Plasma-Lyte 148 (Baxter, Deerfield, IL, USA), Normosol-R (Hospira, Lake Forrest, IL, USA), and Albumex 20 (CSL Behring, King of Prussia, PA, USA). HES solutions are described with regard to their concentration (6%−10%), mean molecular weight (70–480 kDa), and degree of molar substitution (range 0–1; tetrastarch 0.5, hexastarch 0.6).