Table 3 |.

How greater diversity accelerates discovery and translation efforts

Step in research cycle	Potential benefits
Formulate research questions investigating genomic and environmental contributors to health disparities	● Improved study design ● More precise assessment of genetic and environmental risk factors
Provide dedicated funding support	● Increased ability to address challenges to recruitment ● Continuity and stability of research teams
Recruit diverse participants and communities	● Adequate sample sizes for analysis ● Enrolment reflective of population disease burden ● More equitable distribution of benefits of genomic research ● Consensus building and shared oversight
Improve analysis and interpretation by use of foundational genomic data resources	● Higher-quality reference sequences, yielding more accurate variant calls in diverse participants ● Expanded availability of population-specific allele frequencies ● Better imputation and facile data integration, yielding larger sample sizes for analysis ● Fine mapping to identify causal variants ● More accurate identification of clinically relevant variants ● Identification of novel variants
Apply knowledge to health care systems	● Identification of implementation opportunities applicable to all types of health delivery systems ● Implementation of interventions that might otherwise be missed
Increase diversity among researchers and clinicians	● Facilitation of enrolment of diverse participants ● Improved workforce diversity