Comparison 18.

Metronidazole low dose (1g or less) versus standard dose (1.5g or more)

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 No parasitological cure (1‐2 weeks)	2	261	Risk Ratio (M‐H, Fixed, 95% CI)	2.97 [1.92, 4.59]
2 Side effects	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 Any side effect	1	163	Risk Ratio (M‐H, Fixed, 95% CI)	0.70 [0.24, 2.04]
2.2 Nausea/vomiting	2	261	Risk Ratio (M‐H, Fixed, 95% CI)	1.69 [0.29, 9.90]
2.3 Bitter taste	1	163	Risk Ratio (M‐H, Fixed, 95% CI)	0.37 [0.02, 8.99]