Methods | Random allocation to two groups. Blinding could not be maintained after allocation, however no details are given about how allocation concealment was done. |
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Participants | 119 Women attending general practices in Copenhagen, Denmark, who required a gynaecological examination were recruited. Pregnancy, presumed promiscuity, and systemic disorders were reasons for exclusion. |
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Interventions | Metronidazole 200 mg 3 times daily for 7 days versus ornidazole 500 mg 4 tablets by mouth as single dose. Partner treatments were given to the women to take to their partners. |
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Outcomes | Parasitological and clinical cure. Side effects. | |
Notes | Diagnosis by wetmount and culture. Only those verified by culture results were analysed. Excluded wetmount positive culture negatives (10/53 in the metronidazole and 12/66 in the ornidazole groups). Only 1 woman in the ornidazole group was lost to follow up at 1 week, 8 in the ornidazole, and 3 in the metronidazole group were lost at 5 weeks. |