Thin 1979

Methods	Randomised, double blind, placebos used. Individual, numbered treatment packs were randomly arranged to be given to patients. Outcome assessments were blinded.
Participants	Women with trichomoniasis who could attend follow up visits after 2 weeks in London, England.
Interventions	Single dose versus five day regimen: Single dose regimen: Metronidazole 2 g (5 x 400 mg tabs) followed by placebo for 5 days (1 tablet twice daily). Five day regimen: 5 placebo tablets as a single dose followed by metronidazole 400 mg tabs twice daily for 5 days. No partner treatment or notification measures are mentioned. It is not clear whether the women were advised against coitus during the treatment period or not.
Outcomes	Parasitological cure on day 7 and day 14. Side effects.
Notes	Both wetmount smear and culture were used for diagnosis. Loss to follow up on day 14 was 46% and 31% in the single dose and 5 day groups, respectively.