Tinkler 1974

Methods	Randomised, double blind but no placebos used. No mention of blind outcome assessment.
Participants	100 women attending Bristol Royal Infirmary, England. Exclusion criteria: women with more than one partner, who were thought insufficiently intelligent to understand the study, not reliable to take medications as prescribed, and those with partners unwilling to take concurrent medication. Abstinence from sexual intercourse was advised.
Interventions	Metronidazole 200 mg 3 times daily for 7 days versus nimorazole 250 mg twice daily for 6 days, both by mouth.
Outcomes	Parasitological and clinical cure. Side effects.
Notes	Diagnosis by dark field microscopy and culture. Follow up on days 8 and 14. Loss to follow up 4/100 and 7 others excluded for not taking drugs as prescribed.