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. 2002 Apr 22;2002(2):CD003676. doi: 10.1002/14651858.CD003676

Doran 1989.

Methods Randomized (using table of random numbers), parallel, double blind, placebo controlled study
Followed up for 6 days
Participants 68 children aged 1 to 12 years with varicella exanthema
Exclusion criteria: received any medication within 48 hours prior to study entry; history of seizure or other neurologic disorder; receiving long term medication; immunosuppressed
Interventions Paracetamol: 10mg/kg
Placebo
Given as multiple dose at 4 hourly interval for 4 days
Outcomes Time to total scabbing
Itching on day 4
Activity score of the children on day 2
Time to last new vesicle
Time to total healing
Notes Study location: USA
6 (8.8%) children withdrawn or lost to follow up