Doran 1989.
Methods | Randomized (using table of random numbers), parallel, double blind, placebo controlled study Followed up for 6 days |
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Participants | 68 children aged 1 to 12 years with varicella exanthema Exclusion criteria: received any medication within 48 hours prior to study entry; history of seizure or other neurologic disorder; receiving long term medication; immunosuppressed |
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Interventions | Paracetamol: 10mg/kg Placebo Given as multiple dose at 4 hourly interval for 4 days |
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Outcomes | Time to total scabbing Itching on day 4 Activity score of the children on day 2 Time to last new vesicle Time to total healing |
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Notes | Study location: USA 6 (8.8%) children withdrawn or lost to follow up |