Friedman 1990.
Methods | Randomized (using table of random numbers), parallel, open trial Followed up for 1 hour |
|
Participants | 73 children aged 6 weeks to 4 years, rectal temperature 38.9 ºC (102 ºF), with viral and bacterial infection Exclusion criteria: received antipyretic 4 hours prior to study entry; and/or antibiotic in the past 72 hours; history of febrile convulsions; allergy to paracetamol |
|
Interventions | Paracetamol: 10 to 15 mg/kg as single dose Sponging: with tepid water of about 37.8 ºC (100 ºF) for 20 minutes Paracetamol and tepid sponging |
|
Outcomes | Mean temperature over time | |
Notes | Study location: USA No losses to follow up or withdrawals recorded |