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. 2002 Apr 22;2002(2):CD003676. doi: 10.1002/14651858.CD003676

Friedman 1990.

Methods Randomized (using table of random numbers), parallel, open trial
Followed up for 1 hour
Participants 73 children aged 6 weeks to 4 years, rectal temperature 38.9 ºC (102 ºF), with viral and bacterial infection
Exclusion criteria: received antipyretic 4 hours prior to study entry; and/or antibiotic in the past 72 hours; history of febrile convulsions; allergy to paracetamol
Interventions Paracetamol: 10 to 15 mg/kg as single dose
Sponging: with tepid water of about 37.8 ºC (100 ºF) for 20 minutes
Paracetamol and tepid sponging
Outcomes Mean temperature over time
Notes Study location: USA
No losses to follow up or withdrawals recorded