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. 2002 Apr 22;2002(2):CD003676. doi: 10.1002/14651858.CD003676

Kauffman 1992a.

Methods Randomized, double blind placebo controlled
Follow up: antipyretic effect for 8 hours; adverse events for 24 hours
Participants 37 children aged 2 to 12 years with intercurrent febrile illness, oral temperature at ≥ 38.3 ºC at least one hour before enrollment
Interventions Paracetamol: 10mg/kg
Ibuprofen: 7.5 or 10mg/kg; placebo
Outcomes Percentage decrease in temperature from baseline
Area under the curve of percentage decrease in temperature against time
Treatment failures and adverse events
Notes Study location: USA
Treatment failures were treated with 10mg/kg of paracetamol regardless of original treatment group