Kramer 1991.

Methods	Randomized (table of random numbers), parallel, double blind, placebo controlled Follow up: until fever free for at least 24 hours
Participants	304 children aged 6 months to 6 years, rectal temperature ≥ 38 ºC with viral infection Exclusion criteria: onset >4 days; bacterial infection; history of convulsion; fever ≥ 41 ºC
Interventions	Paracetamol: 10 to 15mg/kg given 4 hourly versus placebo
Outcomes	Mean duration of fever Mean duration of other symptoms Improvement in comfort/ behaviour
Notes	Study location: Canada 79 (26%) children randomized participants dropped