Steele 1970.
Methods | Quasi‐randomized (using serially numbered envelopes), parallel, placebo controlled, partially blinded (physical method arm not blinded) Followed up for 2 hours |
|
Participants | 130 children aged 6 months to 5 years, rectal temperature 39.4 ºC or more, lasting more than 3 days, of viral and bacterial origin Exclusion criteria: received antipyretic 4 hours before study entry |
|
Interventions | Paracetamol (alone or with sponging): 80mg, 160mg, 240mg, and 320mg for ages 6 to 18, 18 to 30, 30 to 48, and 48 to 60 months respectively Mechanical: sponging with tepid water (excluding face and head); 2 other mechanical interventions: sponging with ice water or alcohol plus water were also applied |
|
Outcomes | Percentage with temperature ≤ 38.3 ºC at 1 and 2 hours; percentage with comfort rated as good, fair, or poor | |
Notes | Study location: Hawaii No losses to follow up or withdrawals recorded |