Walson 1989.

Methods	Randomized (using block randomization), parallel, double blind, placebo controlled trial Followed p for 8 hours
Participants	127 children aged 2 to 11 years, oral temperature 38.3 to 40 ºC, (diagnosis not specified) Exclusion criteria: received antipyretic 8 hours before study entry; had prestudy salicylate or paracetamol of >50mg/L or >5mg/L respectively; hypersensitivity to medications; history of gastrointestinal tract, renal, liver, cardiopulmonary diseases; convulsive disorders; vomiting within 24 hours before study entry; dehydration
Interventions	Paracetamol:10mg/kg Ibuprofen: 5mg/kg and 10mg/kg; placebo; given as single dose.
Outcomes	Mean temperature over time Mean percent reduction in temperature Area under percent reduction‐time curve Adverse events
Notes	Study location: USA 9 (7.1%) children withdrawn or lost to follow up Antibiotics allowed to participants that required them