Agbolosu 1997.
Methods | Randomized (using block randomization), parallel, open trial Followed up for 2 hours |
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Participants | 80 children aged 6 to 60 months, axillary temperature 38.5 to 40 ºC with urinary tract infection and/or malaria Exclusion criteria: received antipyretic 2 hours prior to study entry; requiring admission; urgent investigation; or emergency treatment |
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Interventions | Paracetamol: 15mg/kg given as single dose Sponging: from head to toe (except scalp) until temperature is <38 ºC, using tepid water (temperature range 28 to 34 ºC) at ambient temperature 21 to 32 ºC |
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Outcomes | Mean temperature over time Mean fall in temperature by group Proportion of children whose temperature fell to <38.5 ºC at different time intervals |
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Notes | Study location: Malawi A thin layer of water left on the body of the children receiving tepid sponging until temperature fell below 38.5 ºCs C No losses to follow up or withdrawals recorded |