Steele 1970

Methods	Generation of allocation sequence: randomized (method not specified but used serially numbered envelopes) Allocation concealment: adequate Blinding: parallel, placebo‐controlled trial Length of follow up: 2 hours
Participants	130 children aged 6 months to 5 years, rectal temperature 39.4 °C or more, lasting more than 3 days, of viral and bacterial origin Exclusion criteria: received antipyretic 4 hours before study entry
Interventions	1. Placebo (n = 15) 2. Tepid water sponging plus placebo (n = 15) 3. Paracetamol alone (n = 25) 4. Tepid sponging plus paracetamol (n = 25) 5. Iced water plus paracetamol (n = 25) 6. Alcohol in water plus paracetamol (n = 25) Paracetamol dose: 80 mg (6 to 18 months), 160 mg (18 to 30 months), 240 mg (30 to 48 months) and 320 mg (48 to 60 months)
Outcomes	Percentage with temperature </= 38.3 °C at 1 and 2 hours; percentage with comfort rated as good, fair, or poor
Notes	Study location: Honolulu, Hawaii No losses to follow up or withdrawals recorded