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. 2008 Oct 8;2008(4):CD004912. doi: 10.1002/14651858.CD004912.pub3

Comparison 2. Artesunate plus mefloquine (AS+MQ) vs quinine (QN).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Treatment failure at day 63 (excludes new infections, detected by PCR) 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
2 Anaemia 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
2.1 On admission 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.2 Day 7 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.3 Day 28 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.4 Day 42 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.5 Day 63 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3 Nervous system adverse events 2   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
3.1 Abnormal neurology 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.2 Blurring vision 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.3 Dizziness 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.4 Headache 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.5 Tinnitus 2   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.6 Vertigo 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4 Gastrointestinal adverse events 2   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
4.1 Abdominal pain 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4.2 Anorexia 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4.3 Nausea 2   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4.4 Vomiting 2   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
5 Other adverse events 2   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
5.1 Hypoglycaemia 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
5.2 Muscle and joint pain 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
5.3 Palpitations 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
6 Low birthweight 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
7 Mean birthweight 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
8 Abortion 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
9 Neonatal jaundice 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected