Lee 2001.

Methods	Randomized controlled trial, non‐blinded; 1 centre Duration: 6 months, October 1999 to March 2000
Participants	Inclusion criteria: inpatients; consecutive admissions aged 6‐60 months; diarrhoea < 5 days and > 3 watery stools in last 24 hours. Average dehydration about 5% in both groups. Exclusion criteria: bloody stools, antidiarrhoeal or antiperistaltic drugs; children receiving lactose‐free, protein hydrolysated formula for malabsorptive disorder; compromised immune system. Number completing study: 50/50 (100%) probiotic and 50/50 (100%) control group.
Interventions	Lyophilized L. acidophilus and Bifidobacteria infantis (Infloran Berna; 3 x 109 of each organism/day for 4 days) No additional treatment All children had IV fluids because of vomiting. Interventions administered after initial fluid therapy.
Outcomes	Stool frequency by day of intervention Duration of diarrhoea (time until the last watery stool) Recovery rate on day 2 No comment regarding adverse effects.
Notes	Study location: Taiwan (low child and adult mortality). Cause of diarrhoea: bloody diarrhoea excluded. Nutritional status: no data presented. Hydration status: % average dehydration 4.3 (SD 1.5) in probiotic and 4.0 (1.4) in control group. Source of funding: not stated
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Unclear risk	Not described
Allocation concealment?	Unclear risk	Not described
Blinding? All outcomes	Unclear risk	Probably open study; no placebo
Incomplete outcome data addressed? All outcomes	Low risk	Follow up ≥ 90% in both groups