Manyando.

Trial name or title	Establishing Effectiveness of Daily Co‐trimoxazole Prophylaxis For Prevention of Malaria in Pregnancy
Methods	Randomized study
Participants	Expected enrolment: sample size not given. Minimum age: All HIV pregnant women, no age limit given. Inclusion criteria: HIV positive and HIV negative pregnant women, Hb > 7 g/dl, gestational age between 16 and 28 weeks. Exclusion criteria: Severe anaemia (Hb<7 g/dl) and HIV women already on cotrimoxazole
Interventions	Intervention: co‐trimoxazole prophylaxis Control: sulfadoxine‐pyrimethamine
Outcomes	1. Placental parasitaemia 2. Adverse reactions. 3. Parasitemia at delivery 4. Maternal illness 5. Birth weight 6. Gestational age
Starting date	April 2010
Contact information	Christine Manyando, MD Tel: 260 212 621732 cmanyando@yahoo.com
Notes	NCT01053325

AIDS = Acquired Immunodeficiency syndrome
 Hb = haemoglobin
 HIV = Human Immunodeficiency Virus
 IPTp = Intermittent Preventive Treatment in pregnancy
 MTCT = mother‐to‐child HIV transmission