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. 2013 Jan 31;2013(1):CD008300. doi: 10.1002/14651858.CD008300.pub2
Methods Randomized controlled trial
Duration: 7 months, from June 1996 to January 1997
Participants Number: 45 enrolled infants (30 included in this review)
Inclusion criteria: ipsilateral axillar or supraclavicular lymphadenitis (>1.5 cm) without suppuration
Exclusion criteria: abscess formation
Interventions Group 1: erythromycin (40 mg/kg/day PO for one month)
Group 2: locally instilled streptomycin (20 mg/kg) ‐ group not included in this review
Group 3: no intervention
Outcomes Clinical failure (regression of the lesion not achieved)
Notes Location: Turkey
Setting: community‐based trial
Source of funding: not described
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) All outcomes High risk Open study
Blinding of outcome assessment (detection bias) All outcomes Unclear risk Outcome assessment not blinded but measured in centimetres
Incomplete outcome data (attrition bias) All outcomes Low risk No patients were lost to follow‐up
Selective reporting (reporting bias) Unclear risk Insufficient information to permit judgement
Other bias Unclear risk There was insufficient information to assess whether an important risk of bias exists