Methods | Randomized controlled trial Duration: 7 months, from June 1996 to January 1997 |
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Participants | Number: 45 enrolled infants (30 included in this review) Inclusion criteria: ipsilateral axillar or supraclavicular lymphadenitis (>1.5 cm) without suppuration Exclusion criteria: abscess formation |
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Interventions | Group 1: erythromycin (40 mg/kg/day PO for one month) Group 2: locally instilled streptomycin (20 mg/kg) ‐ group not included in this review Group 3: no intervention |
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Outcomes | Clinical failure (regression of the lesion not achieved) | |
Notes | Location: Turkey Setting: community‐based trial Source of funding: not described |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Open study |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Outcome assessment not blinded but measured in centimetres |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No patients were lost to follow‐up |
Selective reporting (reporting bias) | Unclear risk | Insufficient information to permit judgement |
Other bias | Unclear risk | There was insufficient information to assess whether an important risk of bias exists |