Gazala 1988.

Methods	Randomized controlled trial
Participants	Number: 90 enrolled Inclusion criteria: 1 to 12 months, acute (<4 days duration) watery (at least 4 watery stools per day) diarrhoea, mild dehydration
Interventions	1. Refeeding was started after 6 hours of oral rehydration with ORS 2. Refeeding was started after 24 hours of rehydration.
Outcomes	Percentage weight gain, duration of diarrhoea, number of infants admitted to the hospital
Setting	Private out‐patient trial Location: Primary care clinic in Rahat, Israel
Notes	Clinical features were assessed at 24 hours and 2 weeks following the initial visit We assumed that the reported number of infants admitted to the hospital are interval numbers between the 2 follow‐up evaluations Thirty percent of the infants were lost to follow‐up during the 2‐week period Percentage weight change was reported but not its SD
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	The study started on Sunday and infants were randomly assigned, starting on the last day of the week (Friday), to either group by flipping a coin, then alternated everyday. The daily change was to minimize mothers belonging to one group from influencing other mothers in a different group.
Allocation concealment (selection bias)	High risk	Those assigning will be able to decipher the next treatment allocation for the subsequent days after the initial flipping of the coin
Blinding (performance bias and detection bias) All outcomes	High risk	Participants and caregivers were not blinded, but it was not mentioned if the outcome assessors were blinded
Incomplete outcome data (attrition bias) All outcomes	High risk	16 out of 53 and 11 out of 37 in the early and late refeeding group, respectively, were not reported in the assessment of outcome 2 weeks following initial visit
Selective reporting (reporting bias)	Unclear risk	No details given in trial report
Other bias	High risk	Thirty percent of patients lost to follow up