Avila‐Romay 1991.

Methods	Design: randomized controlled trial Generation of allocation sequence: "randomly assigned" Allocation concealment: unclear Blinding: unclear Inclusion of randomized participants in the analysis: 100%
Participants	Number: 51 cases and 60 contacts enrolled (children 6 to 17 years old; sex not stated) Inclusion criteria: clinically compatible lesions associated with itching Exclusion criteria: secondary infection
Interventions	1. 10% sulfur in pork fat with 1% salicylic acid as preservative (25 cases and 28 contacts) 2. 10% sulfur in cold cream (26 cases and 32 contacts) Both medications applied nightly for 3 nights then once 3 nights later, average dose 7 g Both medications applied by the patients from shoulders to feet for about 5 minutes, under supervision of a physician
Outcomes	1. Number of participants clinically cured at 10 days (defined as absence of cutaneous lesions and itching) 2. Secondary cutaneous reactions in cases and contacts Not included in this review: 3. Patient preference (not further defined)
Notes	Location: Mexico; participants from a house for orphan children Date: not stated 60 contacts also randomly assigned to treatment with sulfur in either pork fat or cold cream