Brooks 2002.
Methods | Design: randomized controlled trial Generation of allocation sequence: computer generated Allocation concealment: unclear Blinding: investigators Inclusion of randomized participants in the analysis: 73% (30/110 lost to follow up) |
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Participants | Number: 110 enrolled (children 6 months to 14 years old; sex not stated) Inclusion criteria: clinically diagnosed scabies Exclusion criteria: treatment for scabies within previous 2 months; major intercurrent illness; history of meningitis or neurological illness |
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Interventions | 1. Oral ivermectin 200 µg/kg bodyweight single dose (55 participants) 2. 10% benzyl benzoate applied neck to toe overnight (55 participants) | |
Outcomes | 1. Number of participants clinically cured at 3 weeks (defined as absence of skin lesions)
2. Number of participants with persistence of night‐time itch at 3 weeks
3. Adverse events Not included in this review 4. Itch severity 5. Numbers of lesions |
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Notes | Location: Vanuatu Date: January to April 2001 Family contacts treated with same drug as the participant Author confirmed equal numbers of participants randomized to each intervention |