Macotela‐Ruiz 1993.

Methods	Design: randomized controlled trial Generation of allocation sequence: unclear Allocation concealment: unclear Blinding: participants and outcomes assessor Inclusion of randomized participants in the analysis: 100%
Participants	Number: 55 enrolled (aged over 5 years;18 males mean age 25 +/‐ 4 years, 37 females mean age 24 +/‐ 16 years) Inclusion criteria: clinical diagnosis of scabies Exclusion criteria: pregnancy; breastfeeding; impaired renal function; impaired liver function; treatment for scabies within previous 3 weeks
Interventions	1. Oral ivermectin 200 µg/kg bodyweight single dose (29 participants) 2. Placebo (26 participants)
Outcomes	1. Number of participants clinically cured at 7 days (defined as absence of itching and no dermatologically active lesions) 2. Adverse events
Notes	Location: Mexico Date: not stated Trial stopped at 7 days as ivermectin group significantly clinically better