Madan 2001.
Methods | Design: randomized controlled trial Generation of allocation sequence: unclear Allocation concealment: unclear Blinding: outcomes assessor Inclusion of randomized participants in the analysis: 75% (50/200 lost to follow up) |
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Participants | Number: 200 enrolled (aged over 5 years; 132 males, 68 females) Inclusion criteria: clinical diagnosis of scabies (defined as nocturnal itching and/or family contact with similar complaint and/or typical lesions) Exclusion criteria: pregnancy; breastfeeding; severe cardiovascular, respiratory, or central nervous system disorders |
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Interventions | 1. Oral ivermectin 200 µg/kg bodyweight single dose (100 participants) 2. 1% lindane lotion applied neck to toe and left on overnight (100 participants) | |
Outcomes | 1. Number of participants clinically cured at 4 weeks (defined as no signs or symptoms of scabies)
2. Adverse events Not included in this review: 3. Number of participants clinically cured at 2 weeks 4. Number of patients with good improvement at 4 weeks |
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Notes | Location: India Date: not stated Microscopic confirmation of diagnosis in 170/200 (85%) of participants Family contacts treated with 25% benzyl benzoate lotion for 3 days |