| Trial | No. patients (%) |
| Agra 1981 | Not available |
| East Africa 1978 | 64/619 (10.3) |
| Germany 1986 | None (excluded) |
| Hong Kong1989 | 83/542 (15.3) |
| Hong Kong 1979 | 44/274 (16.1) |
| Singapore | 33/363 (9.1) |
| S. India 1986 | 64/469 (13.6) |
| S. India 1983 | 98/628 (15.6) |
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