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| Methods | Inidividual randomization. | |
| Participants | 679 Chinese men with silicosis in Hong Kong. Most 45‐64, 63% current smokers, 94% >10mm. Criteria: silicosis diagnosis, no history TB, no evidence TB, negative sputum microscopy and culture. |
|
| Interventions | INH 300 mg daily 6 months; Rifampin 600 mg daily 12 weeks; INH + Rif 12 weeks; placebo. | |
| Outcomes | 1. Active tuberculosis | |
| Notes | All had abnormal chest x‐rays. Only the INH and placebo arms included in this review (total 199). |
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