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| Methods | Randomization by family unit. | |
| Participants | 2,824 household contacts of known tuberculosis cases (prevalent cases) in USA. 1/3 children; 55% PPD< 5mm; 60% black. |
|
| Interventions | Isoniazid 300 mg daily for one year. | |
| Outcomes | 1. Active tuberculosis 2. Extrapulmonary tuberculosis 3. Deaths | |
| Notes | — | |
